Bincy P. Abraham, MD, MS reviewing Vavricka SR, et al. Am J Gastroenterol 2025 Dec 16.

Environmental factors, including hypoxia, may contribute to worsening disease activity in inflammatory bowel disease (IBD). Researchers assessed outcomes after exposing patients with IBD and healthy controls to simulated hypoxia in a hypobaric low-pressure chamber for 3 hours.

Marietta Iacucci, MD, PhD, FASGE reviewing Bezzio C, et al. J Crohns Colitis 2025 Dec 23.

Evidence shows that appropriate intestinal ultrasound (IUS) training reduces performance gaps between less experienced and expert operators, but data on parameter-specific learning curves remain limited. These authors characterized learning curves and competency thresholds for basic and advanced IUS parameters.

David H. Bruining, MD, FASGE reviewing Rimmer P, et al. Gastroenterology 2026 Mar.

Disruption of the gut microbiome has been linked to the development of IBD and considered a potential diagnostic and prognostic marker. Researchers conducted a systematic review and performed a novel secondary bioinformatic reanalysis of sequence data related to the gut microbiome at IBD onset.